A comparative study between Dexmedetomidine infusion and Propofol infusion for maintenance in patients undergoing Functional Endoscopic Sinus Surgery under General Anaesthesia

Functional Endoscopic sinus surgery (FESS), visibility is often affected by intra-nasal bleeding, which can be influenced by various anaesthetics. We conducted a prospective randomized controlled study in 60 ASA I and ASA II patients between 18-60 years of age undergoing functional endoscopic sinus surgery under general anesthesia. Aim: To study and compare hemodynamics, blood loss and operative field visibility between Dexmedetomidine infusion and Propofol infusion when used for maintenance in FESS surgeries. Material and Method: Institutional ethics committee approval and informed written consent were taken. Patients were randomly divided into Group D (Dexmedetomidine) and Group P(Propofol) with 30 patients each. Group D received 0.5mcg/kg/hr Dexmedetomidine and Group P received 100mcg/kg/hr Propofol.for maintenance introperatively. Patients hemodynamics, blood loss were assessed and operatively filed visibility were assessed using a 6 point scale given by Fromme et al and Boezart et al. Results: Demographically both groups were comparable. Hemodynamics in both the groups were comparable with better control on heart rate in Group D. Blood loss was less in Group D as compared to Group P. The operative field visibility was also better in Group D. Conclusion: Dexmedetomidine and Propofol both provide stable intraoperative hemodynamics. However Dexmedetomidine gives better operative filed visibility and decreases the blood loss.